Package: qpNCA 1.1.6
qpNCA: Noncompartmental Pharmacokinetic Analysis by qPharmetra
Computes noncompartmental pharmacokinetic parameters for drug concentration profiles. For each profile, data imputations and adjustments are made as necessary and basic parameters are estimated. Supports single dose, multi-dose, and multi-subject data. Supports steady-state calculations and various routes of drug administration. See ?qpNCA and vignettes. Methodology follows Rowland and Tozer (2011, ISBN:978-0-683-07404-8), Gabrielsson and Weiner (1997, ISBN:978-91-9765-100-4), and Gibaldi and Perrier (1982, ISBN:978-0824710422).
Authors:
qpNCA_1.1.6.tar.gz
qpNCA_1.1.6.zip(r-4.5)qpNCA_1.1.6.zip(r-4.4)qpNCA_1.1.6.zip(r-4.3)
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qpNCA_1.1.6.tar.gz(r-4.5-noble)qpNCA_1.1.6.tar.gz(r-4.4-noble)
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qpNCA.pdf |qpNCA.html✨
qpNCA/json (API)
| # Install 'qpNCA' in R: |
| install.packages('qpNCA', repos = c('https://huismanj.r-universe.dev', 'https://cloud.r-project.org')) |
This package does not link to any Github/Gitlab/R-forge repository. No issue tracker or development information is available.
Last updated 4 years agofrom:03f47c2925. Checks:1 OK, 8 WARNING. Indexed: yes.
| Target | Result | Latest binary |
|---|---|---|
| Doc / Vignettes | OK | Mar 13 2025 |
| R-4.5-win | WARNING | Mar 13 2025 |
| R-4.5-mac | WARNING | Mar 13 2025 |
| R-4.5-linux | WARNING | Mar 13 2025 |
| R-4.4-win | WARNING | Mar 13 2025 |
| R-4.4-mac | WARNING | Mar 13 2025 |
| R-4.4-linux | WARNING | Mar 13 2025 |
| R-4.3-win | WARNING | Mar 13 2025 |
| R-4.3-mac | WARNING | Mar 13 2025 |
Exports:calc.ctmaxcalc.parcalc.par.thcorrect.conccorrect.loqcorrect.timeest.thalfplot_regqpNCAtab.corr
Dependencies:clicolorspacecpp11dplyrevaluatefansifarvergenericsggplot2gluegtablehighrisobandknitrlabelinglatticelifecyclemagrittrMASSMatrixmgcvmunsellnlmepillarpkgconfigpurrrR6RColorBrewerrlangscalesstringistringrtibbletidyrtidyselectutf8vctrsviridisLitewithrxfunyaml
qpNCA User Guide
Rendered fromUser_Guide.rmdusingknitr::rmarkdownon Mar 13 2025.Last update: 2021-07-13
Started: 2021-07-13
full-nca-analysis.rmd
Rendered fromExample-full-nca-analysis.rmdusingknitr::knitron Mar 13 2025.Last update: 2021-07-13
Started: 2021-07-13
stepwise-nca-analysis.rmd
Rendered fromExample-stepwise-nca-analysis.rmdusingknitr::knitron Mar 13 2025.Last update: 2021-07-13
Started: 2021-07-13
Parameter Guidelines
Rendered fromParameter_Guidelines.rmdusingknitr::rmarkdownon Mar 13 2025.Last update: 2021-07-13
Started: 2021-07-13
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| Calculate Cmax and Tmax | calc.ctmax |
| Calculate NCA Parameters | calc.par |
| Calculate Lambda_z Parameters | calc.par.th |
| Check qpNCA function arguments for validity | check.input |
| Correct Missing Concentration | correct.conc |
| Impute Concentrations Below the Limit of Quantitation | correct.loq |
| Correct Concentrations for Time Deviations | correct.time |
| Calculate Lambda_z and Elimination Half-life | est.thalf |
| Create File Name for Regression Plots | filenamefun |
| Interpolate Concentrations | interpol |
| Estimate Lagging and Leading Times and Concentrations | lag_lead |
| Plot Regression Curves | plot_reg |
| Perform Non-compartmental Analysis | qpNCA |
| Tabulate Corrections | tab.corr |
| Create Title for Regression Plots | titlefun |
| Calculate Area Under the Curve Using Trapezoids | trap |
| Calculate Area Under the Moment Curve Using Trapezoids | trapm |
